The purpose of this study was to assess the lifting performance of boys (N = 12; age 11.3 +/- 0.8 yr), teens (N = 13; age 13.6 +/- 0.6 yr), and men (N = 17; age 21.4 +/- 2.1 yr) to various rest interval (RI) lengths on the bench press exercise. Each subject performed 3 sets with a 10 repetition maximum load and a 1, 2, and 3 min RI between sets. Significant differences in lifting performance between age groups were observed within each RI for selected sets with boys and teens performing significantly more total repetitions than adults following protocols with 1 min (27.9 +/- 3.1, 26.9 +/- 3.9, and 18.2 +/- 4.1, respectively), 2 min (29.6 +/- 1.0, 27.8 +/- 3.5, and 21.4 +/- .1, respectively) and 3 min (30.0 +/- 0.0, 28.8 +/- 2.4, and 23.9 +/- 5.3, respectively) RIs. Significant differences in average velocity and average power between age groups were also observed. These findings indicate that boys and teens are better able to maintain muscle performance during intermittent moderate-intensity resistance exercise as compared with men.