Abstract
Perilla frutescens is a food plant widely used in Asian cuisine. This plant was investigated for its interesting taste and somatosensory properties. Perillaldehyde and perillaketone are among the components of the aromatic extracts from P. Frutescens. These compounds were shown here to activate the cloned TRPA1 channel when expressed in an heterologous cell system and are therefore suggested to be responsible for the chemesthetic properties of this plant.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antioxidants / isolation & purification
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Antioxidants / pharmacology
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Humans
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Monoterpenes / isolation & purification
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Monoterpenes / pharmacology*
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Perilla frutescens / chemistry*
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Plant Extracts / isolation & purification
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Plant Extracts / pharmacology
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Taste*
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Transfection
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Transient Receptor Potential Channels / agonists*
Substances
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Antioxidants
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Monoterpenes
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Plant Extracts
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Transient Receptor Potential Channels
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perillaldehyde
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perilla ketone