Th17 lymphocytes have been recently identified as a novel subset of CD4+ cells. It has been defined that IL-17, the main product of Th17, plays an important role in immunity against parasitic infection. There is a two-way influence between Th17 and cytokine network: on one hand Th17 consummate cytokine network, on the other hand many cytokines regulate Th17's activity in parasitic infection. In the anti-parasitic infection process, Th17 cells protect host or promote inflammation, even cause immune pathogenesis in different cases, which comprise host's immune state, the burden of parasitic infection, as well as the treatment.