SREBPs: protein interaction and SREBPs

FEBS J. 2009 Feb;276(3):622-7. doi: 10.1111/j.1742-4658.2008.06807.x.

Abstract

Sterol regulatory element-binding proteins (SREBPs) are tightly controlled by various mechanisms, including intracellular localization, protein processing, limited proteolysis, post-translational modifications and interaction with associated proteins. Here, I review the regulatory mechanisms of SREBP activity through the interaction with various kinds of protein.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Nucleus / metabolism
  • Cytosol / metabolism
  • Endoplasmic Reticulum / metabolism
  • Humans
  • Protein Binding
  • Sterol Regulatory Element Binding Proteins / genetics
  • Sterol Regulatory Element Binding Proteins / metabolism*
  • Transcription, Genetic / genetics

Substances

  • Sterol Regulatory Element Binding Proteins