Abstract
Objective:
To study chemical constituents of antibacterial activity fraction of Angelica polymorpha.
Methods:
Compounds were isolated by repeatedly silica gel column chromatography and recrystallization. Their structures were identified by physical and chemical evidences and spectral methods.
Results:
Seven compounds were obtained from the antibacterial activity fraction, their structures were elucidated as: bisabolangelone(I), isoimperatorin (II), oxypeucedanine(III), isooxypeucedanine(IV), oxypeucedanin hydrate(V), bergapten(VI), pabulenol(VII).
Conclusion:
Bisabolangelone(I) is obtained from this plant for the first time. Compound (II)-(VII) belong to linear furanocourmarins.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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5-Methoxypsoralen
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Angelica / chemistry*
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / isolation & purification
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Chromatography, High Pressure Liquid
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Coumarins / chemistry
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Coumarins / isolation & purification
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Ficusin / chemistry
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Ficusin / isolation & purification
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Furocoumarins / chemistry
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Furocoumarins / isolation & purification*
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Methoxsalen / analogs & derivatives
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Methoxsalen / chemistry
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Methoxsalen / isolation & purification
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Plant Roots / chemistry
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Plants, Medicinal / chemistry*
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Sesquiterpenes / chemistry
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Sesquiterpenes / isolation & purification*
Substances
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Anti-Bacterial Agents
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Coumarins
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Furocoumarins
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Sesquiterpenes
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bisabolangelone
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isoimperatorin
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pabulenol
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5-Methoxypsoralen
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Ficusin
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Methoxsalen