Albee's social justice approach to prevention offers a framework for understanding the detrimental effect of heterosexism on lesbian, gay, and bisexual (LGB) people. Minority stress models likewise address the role of discrimination and other social injustices in contributing to psychological distress in minority populations. This article describes Albee's framework in the context of minority stress theory as it applies to LGB people and suggests activities mental health professionals can engage in to help prevent the psychological consequences of heterosexism.