Near-tubular fiber bundle segmentation for diffusion weighted imaging: segmentation through frame reorientation

Neuroimage. 2009 Mar;45(1 Suppl):S123-32. doi: 10.1016/j.neuroimage.2008.11.001. Epub 2008 Nov 13.

Abstract

This paper proposes a methodology to segment near-tubular fiber bundles from diffusion weighted magnetic resonance images (DW-MRI). Segmentation is simplified by locally reorienting diffusion information based on large-scale fiber bundle geometry. Segmentation is achieved through simple global statistical modeling of diffusion orientation. Utilizing a modification of a recent segmentation approach by Bresson et al. allows for a convex optimization formulation of the segmentation problem, combining orientation statistics and spatial regularization. The approach compares favorably with segmentation by full-brain streamline tractography.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Algorithms
  • Brain / anatomy & histology*
  • Diffusion Magnetic Resonance Imaging*
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Models, Statistical
  • Neural Pathways / anatomy & histology