The recurrent goiter: prevention and management

Ann Ital Chir. 2008 Jul-Aug;79(4):247-53.

Abstract

Aim of the study: Conservative surgery of thyroid is followed by recurrence in 2 to 70% of cases in an 8-20 years period. The surgical treatment of such recurrence is affected by higher morbidity than a primary total thyroidectomy. We wanted verify in our series this difference and discuss motivations for conservative or radical surgery of goiter.

Materials and methods: We compared a series of 91 primary total thyroidectomy (A) with 11 cases of total thyroidectomy for recurrence (B) performed between 2001 and 2005.

Results: Postoperative complications were: Transient hypocalcemia 7 (7.69%) in A and 3 (27%) in B, Permanent hypocalcemia only 1 (9%) in B, Transient RLN deficit 2 (2.1%) in A and 2 (18.1%) in B.

Conclusions: Due to the need of a lifelong therapy with LT4 no utility is observed in conservative surgery of thyroid. Further, in primary surgery, differences in incidence of perioperative complications cannot be advocated to justify a conservative approach. Sophisticated technologies are not able to prevent all damages to parathyroid or to recurrent nerves when operating on recurrent goiter. Our experience confirms the results of a review of literature on this topic: the best management of recurrent goiter is its prevention by primary total thyroidectomy.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Clinical Trials as Topic
  • Female
  • Follow-Up Studies
  • Goiter / surgery*
  • Humans
  • Hypocalcemia / diagnosis
  • Hypocalcemia / etiology
  • Length of Stay
  • Male
  • Postoperative Complications / diagnosis
  • Recurrent Laryngeal Nerve Injuries
  • Reoperation
  • Secondary Prevention
  • Thyroidectomy*
  • Thyroxine / administration & dosage
  • Thyroxine / therapeutic use
  • Time Factors

Substances

  • Thyroxine