Profitability of our lung retrieval program from non heart beating donors

Eur J Cardiothorac Surg. 2009 Feb;35(2):287-91; discussion 291-2. doi: 10.1016/j.ejcts.2008.10.030. Epub 2008 Dec 11.

Abstract

Objective: In 2002 the first lung transplant from non heart beating (NHB) donors took place in Madrid. The objective of this study was to analyse our Maastricht type I NHB lung donors retrieval program and to check out its profitability.

Materials and methods: Based on the NHB lung donors retrieval program carried out at Hospital Clínico San Carlos (Madrid) in association with Hospital Puerta de Hierro (Madrid), all lung donors from the beginning of the program from June 2002 to December 2006 have been analysed. When faced with a case of sudden death, advanced life support manoeuvres are initiated before 15 min. If the patient meets a given set of criteria, code 0/9 is activated. Arrival time to the hospital cannot exceed 90 min. Femoral artery and vein are cannulated, extracorporeal circulation is started and lungs are preserved. After the relatives' and judicial authorisation lungs are retrieved.

Results: Out of a total of 322 occurrences of code 0/9, 43 lung retrievals and 25 implants were reported. A total of 95% of donors were male, with an average age of 41 years and 91% with blood group A or O. 2004 saw the highest number of retrievals (14). January, May and December showed the highest number of retrievals. Incidence of sudden deaths was higher from 7 to 10 a.m. and from 7 to 10 p.m. Twenty-three implants at Hospital Puerta de Hierro and three more at Hospital Marqués de Valdecilla (Santander) were reported. A considerable amount of preserved lungs, valid for transplant, were not retrieved because of a lack of an appropriate recipient at the time.

Conclusions: A total of 58.1% of preserved lungs were implanted. The ratio of obtained lungs was 11.4% of actual donors and 7.7% of total occurrences. However, this percentage could have been higher if we take into account the number of valid lungs that were not transplanted because of the lack of recipients.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Circadian Rhythm
  • Donor Selection
  • Female
  • Humans
  • Lung Transplantation / statistics & numerical data*
  • Male
  • Middle Aged
  • Practice Guidelines as Topic
  • Program Evaluation
  • Seasons
  • Spain
  • Tissue and Organ Harvesting / methods
  • Tissue and Organ Harvesting / standards
  • Tissue and Organ Procurement / methods
  • Tissue and Organ Procurement / organization & administration*
  • Young Adult