Abstract
Patients taking quinolones as inpatients (n = 55) or outpatients (n = 40) and newly hospitalized patients who were not on quinolone therapy (n = 41) were assessed for fecal carriage of quinolone-resistant Escherichia coli (QREC) strains before and after therapy/hospitalization. Fluoroquinolone use in the previous 6 months was found to be a risk factor for QREC carriage before therapy/hospitalization. The prevalence of QREC strains in fecal flora increased steadily with the duration of quinolone therapy.
MeSH terms
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Adult
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Aged
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Anti-Bacterial Agents / therapeutic use*
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Drug Resistance, Bacterial
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Escherichia coli / drug effects*
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Escherichia coli / genetics
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Escherichia coli Infections* / drug therapy
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Escherichia coli Infections* / epidemiology
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Escherichia coli Infections* / microbiology
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Feces / microbiology*
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Female
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Humans
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Inpatients / statistics & numerical data
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Male
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Middle Aged
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Outpatients / statistics & numerical data
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Prevalence
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Quinolones / therapeutic use*
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Risk Factors
Substances
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Anti-Bacterial Agents
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Quinolones