This article is devoted to answering frequently asked questions from veterinarians, veterinary technicians, and pet owners about urolithiasis and the detection, treatment, and prevention of various types of uroliths from various locations in the urinary tract. It has been divided into the following topics: urolith analysis, urolith types, diagnosis, treatment and prevention, urolith recurrence, urinalysis, diet, water, and miscellaneous. The information is geared toward both professionals (eg, the chemical analysis of uroliths) and pet owners (eg, the practical considerations of diet). It includes photographs of various stones and a checklist of factors that suggest the probable mineral composition of canine uroliths.