Efficacy and safety of on-pump beating heart surgery

Ann Thorac Surg. 2008 Dec;86(6):1914-8. doi: 10.1016/j.athoracsur.2008.07.003.

Abstract

Background: Beating-heart surgery with warm blood perfusion, instead of cardioplegic solution, has been widely accredited to be a feasible technique in the cardiac operation. However, few studies have addressed the efficacy and safety of on-pump beating-heart surgery, especially with large numbers of patients. In this study, the efficacy and safety of on-pump beating-heart surgery was evaluated by surveying 701 patients with cardiac disease.

Methods: Preoperative risk factors, intraoperative techniques, and postoperative complications were documented and evaluated in 701 consecutive patients (from January 1, 2002, to December 30, 2006) who underwent beating-heart surgery with continuous antegrade or retrograde warm blood perfusion at The People's Hospital of Guangxi Zhuang Autonomous Region.

Results: Among the 701 patients with beating-heart surgery, antegrade perfusion was used in 556 patients (79.32%); retrograde perfusion was used in 40 patients (5.71%); and retrograde perfusion followed by antegrade perfusion was performed in 93 patients (13.27%). Cardioplegic arrest was required in 12 patients (1.71%) for inadequate visualization. In 4 of 701 patients (0.57%) low cardiac output syndrome occurred. Hemoglobinuria occurred in 16 patients (2.28%). No air embolization or permanent high-degree atrioventricular block occurred in these patients. The crude mortality of the surveyed patients was 2.43% (17 of 701).

Conclusions: Our results indicate that on-pump beating-heart surgery is a relatively safe and reliable technique for treatment of cardiac diseases.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Cardiopulmonary Bypass / methods*
  • Cardiopulmonary Bypass / mortality
  • Cardiovascular Diseases / diagnosis
  • Cardiovascular Diseases / mortality
  • Cardiovascular Diseases / surgery*
  • China
  • Cohort Studies
  • Coronary Artery Bypass, Off-Pump / methods*
  • Coronary Artery Bypass, Off-Pump / mortality
  • Female
  • Follow-Up Studies
  • Heart Defects, Congenital / diagnosis
  • Heart Defects, Congenital / mortality
  • Heart Defects, Congenital / surgery*
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Risk Assessment
  • Sensitivity and Specificity
  • Survival Rate
  • Treatment Outcome