An atlas-based segmentation propagation framework locally affine registration--application to automatic whole heart segmentation

Med Image Comput Comput Assist Interv. 2008;11(Pt 2):425-33. doi: 10.1007/978-3-540-85990-1_51.

Abstract

In this paper, we present a novel registration algorithm for locally affine registrations. This method preserves the anatomical and intensity class relationships between the local regions. A regularisation procedure is used to maintain a global diffeomorphic transformation. Combined with a novel generic method for accurately inverting the final deformation field, we include our techniques within an atlas-based segmentation propagation framework. We applied our method to automatically segment the whole heart from cardiac magnetic resonance images from a cohort of 18 volunteers (acquisition resolution 2 x 2 x 2 mm). The results show that the proposed method provides a robust initialisation for the atlas-based segmentation propagation framework refined with a fluid registration. We validated our approach against other registration strategies, and demonstrated that we improved the accuracy of the whole heart segmentations (1.8 +/- 0.42 mm).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Artificial Intelligence*
  • Heart / anatomy & histology*
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / methods*
  • Magnetic Resonance Imaging / methods*
  • Pattern Recognition, Automated / methods*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Subtraction Technique*