End game strategies towards the total synthesis of vibsanin E, 3-hydroxyvibsanin E, furanovibsanin A, and 3-O-methylfuranovibsanin A

Beilstein J Org Chem. 2008:4:34. doi: 10.3762/bjoc.4.34. Epub 2008 Oct 8.

Abstract

End game synthetic strategy studies towards the total synthesis of the vibsanin type diterpenes, vibsanin E, 3-hydroxyvibsanin E, furanovibsanin A, and 3-O-methylfuranovibsanin A are discussed, with focus on construction of the side chain and peripheral functionality associated with this group of natural products is the current focus of this report.

Keywords: 3-O-methylfuranovibsanin A; 3-hydroxyvibsanin E; Viburnum; diterpenes; furanovibsanin A; natural products; terpenoids; vibsane; vibsanin E.