Lack of specific saxitoxin binding to rat mast cells

Agents Actions. 1991 May;33(1-2):92-3. doi: 10.1007/BF01993135.

Abstract

We studied whether or not mast cells are endowed with specific sodium channels, by using tritiated saxitoxin which binds to site 1 of sodium channels on excitable tissues. Our results suggest that rat pleural and peritoneal mast cells lack specific sodium channels.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Mast Cells / metabolism*
  • Peritoneal Cavity / cytology
  • Pleura / cytology
  • Rats
  • Saxitoxin / metabolism*

Substances

  • Saxitoxin