Proliferative lupus nephritis in a patient with systemic lupus erythematosus and longstanding secondary amyloid nephropathy

Clin Rheumatol. 2009 Jan;28(1):95-7. doi: 10.1007/s10067-008-1025-7. Epub 2008 Oct 22.

Abstract

Secondary amyloidosis is an unusual complication of systemic lupus erythematosus (SLE). We report the case of a 60-year-old woman with SLE and secondary amyloidosis who developed class III proliferative lupus nephritis 13 years after the onset of amyloid nephropathy. The patient was treated with mycophenolate mofetil (1.5 g/day) with a significant improvement in proteinuria.

Publication types

  • Case Reports

MeSH terms

  • Amyloid / metabolism
  • Amyloidosis / complications
  • Amyloidosis / drug therapy
  • Amyloidosis / pathology*
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Female
  • Humans
  • Kidney / metabolism
  • Kidney / pathology*
  • Kidney Glomerulus / metabolism
  • Kidney Glomerulus / pathology
  • Lupus Nephritis / complications
  • Lupus Nephritis / drug therapy
  • Lupus Nephritis / pathology*
  • Middle Aged
  • Mycophenolic Acid / analogs & derivatives
  • Mycophenolic Acid / therapeutic use
  • Proteinuria / drug therapy
  • Treatment Outcome

Substances

  • Amyloid
  • Anti-Inflammatory Agents, Non-Steroidal
  • Mycophenolic Acid