Metabolic syndrome patient compliance with drug treatment

Clinics (Sao Paulo). 2008 Oct;63(5):573-80. doi: 10.1590/s1807-59322008000500002.

Abstract

Objectives: 1) To evaluate the compliance with drug treatment in patients with metabolic syndrome. 2) To determine association between access to and use of medicines, as well as the level of knowledge of cardiovascular risk factors and compliance.

Introduction: Low compliance has been one of the greatest challenges for the successful treatment of chronic diseases. Although this issue has been widely studied in patients with isolated hypertension, diabetes and dyslipidemia, compliance studies involving patients with these concomitant diseases or with metabolic syndrome diagnosis are scarce.

Methods: This was a cross-sectional study involving patients who have been diagnosed with metabolic syndrome according to the IDF criteria. Patients were being treated in a Health-Medical School Center bound to the Public Brazilian Healthcare System. This study was conducted in two phases. Phase I was characterized by analyzing medical records and Phase II involved interviewing the patients. A variation of the Morisky-Green Test was used to evaluate compliance. Compliance was the dependent variable and the independent variables included access to medicines, the use of medicines and the level of knowledge concerning cardiovascular risk factors.

Results: Two hundred and forty-three patients were identified as being eligible for Phase II, and 75 were included in the study. The average level of compliance was 5.44 points (standard deviation of 0.68), on a scale ranging from 1.00 to 6.00 points. There was no statistically meaningful association between independent variables and compliance. The level of patient knowledge of diet and dyslipidemia was considered to be low.

Conclusions: Patients involved in this study exhibited a high level of compliance with drug treatment. Further research is needed to better elucidate the compliance behavior of patients who have been diagnosed with metabolic syndrome.

MeSH terms

  • Adult
  • Aged
  • Antihypertensive Agents / economics
  • Antihypertensive Agents / supply & distribution
  • Antihypertensive Agents / therapeutic use*
  • Body Mass Index
  • Chronic Disease
  • Cross-Sectional Studies
  • Diabetes Mellitus / drug therapy
  • Female
  • Health Knowledge, Attitudes, Practice*
  • Humans
  • Hypertension / drug therapy
  • Hypoglycemic Agents / economics
  • Hypoglycemic Agents / supply & distribution
  • Hypoglycemic Agents / therapeutic use*
  • Income
  • Male
  • Medication Adherence / statistics & numerical data*
  • Metabolic Syndrome / drug therapy*
  • Metabolic Syndrome / economics
  • Middle Aged
  • Risk Factors
  • Waist Circumference

Substances

  • Antihypertensive Agents
  • Hypoglycemic Agents