Abstract
Introduction:
There are few studies investigating the effect of HCV coinfection on HIV-related disease among children.
Methods:
We studied 5 HIV/HCV coinfected children receiving an LPV/r-containing HAART regimen. Their evolution was compared with a control group of 72 HIV-infected children.
Results:
All 5 HIV/HCV-coinfected children achieved sustained immune recovery during the study. Moreover, they showed better viral suppression than the control group. None of the 5 HIV/HCV-coinfected children experienced any adverse effects with the use of LPV/r.
Conclusion:
HIV/HCV coinfection does not reduce the benefits obtained from HAART.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Anti-HIV Agents / administration & dosage
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Anti-HIV Agents / therapeutic use*
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Antiretroviral Therapy, Highly Active*
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Child
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Child, Preschool
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Disease Progression
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Female
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Follow-Up Studies
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HIV Infections / drug therapy
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HIV Infections / epidemiology*
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HIV Protease Inhibitors / administration & dosage
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HIV Protease Inhibitors / therapeutic use
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Hepatitis C / drug therapy
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Hepatitis C / epidemiology*
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Humans
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Infant
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Lopinavir
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Male
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Pyrimidinones / administration & dosage
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Pyrimidinones / therapeutic use*
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Retrospective Studies
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Ritonavir / administration & dosage
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Ritonavir / therapeutic use*
Substances
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Anti-HIV Agents
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HIV Protease Inhibitors
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Pyrimidinones
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Lopinavir
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Ritonavir