Cypermethrin induced modulations in lipid metabolism of freshwater teleost, Tilapia mossambica

Biochem Int. 1991 Mar;23(5):963-7.

Abstract

Significant changes in lipid metabolic profiles were observed in brain, liver and gill tissues of T. mossambica under chronic exposure to sublethal concentrations of cypermethrin. Increase in total lipid, lipase and free fatty acids with decrease in glycerol content suggests simultaneous operation of lipogenesis and lipolysis during cypermethrin stress. Phospholipid levels dropped, while cholesterol content increased in all the tissues as a consequence of cypermethrin toxicity.

MeSH terms

  • Animals
  • Brain / drug effects
  • Brain / metabolism
  • Cell Membrane
  • Cholesterol / analysis
  • Cholesterol / metabolism
  • Fatty Acids, Nonesterified / metabolism
  • Gills / drug effects
  • Gills / metabolism
  • Glycerol / analysis*
  • Glycerol / metabolism
  • Lethal Dose 50
  • Lipase / metabolism
  • Lipid Metabolism*
  • Liver / drug effects
  • Liver / metabolism
  • Perciformes / metabolism*
  • Phospholipids / metabolism
  • Pyrethrins / toxicity*

Substances

  • Fatty Acids, Nonesterified
  • Phospholipids
  • Pyrethrins
  • cypermethrin
  • Cholesterol
  • Lipase
  • Glycerol