Stimulation of B-cell lymphoproliferations with CpG-oligonucleotide DSP30 plus IL-2 is more effective than with TPA to detect clonal abnormalities

MeSH terms

• B-Lymphocytes / pathology*
• Cell Division / drug effects
• Cells, Cultured / drug effects
• Cells, Cultured / ultrastructure
• Chromosome Aberrations
• Chromosome Banding / methods
• Cohort Studies
• Female
• Humans
• In Situ Hybridization, Fluorescence
• Interleukin-2 / pharmacology*
• Karyotyping / methods*
• Leukemia, Lymphocytic, Chronic, B-Cell / genetics
• Leukemia, Lymphocytic, Chronic, B-Cell / pathology
• Lymphocyte Activation / drug effects*
• Lymphoma, B-Cell / genetics
• Lymphoma, B-Cell / pathology
• Lymphoproliferative Disorders / genetics
• Lymphoproliferative Disorders / pathology*
• Male
• Metaphase
• Mitogens / pharmacology*
• Oligonucleotides / pharmacology*
• Tetradecanoylphorbol Acetate / pharmacology