alpha-glucosidase inhibitors from Garcinia brevipedicellata (Clusiaceae)

Chem Pharm Bull (Tokyo). 2008 Oct;56(10):1466-9. doi: 10.1248/cpb.56.1466.

Abstract

In our continuous search for alpha-glucosidase inhibitors from plants, four new depsidones named brevipsidones A-D (1-4) were isolated from stem bark of Garcinia brevipedicellata together with known damnacanthal, scopoletin and a mixture of stigmasterol and beta-sitosterol. Structural elucidations were made by spectroscopic analyses including 2D-NMR data.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzopyrans / isolation & purification
  • Benzopyrans / pharmacology*
  • Cameroon
  • Enzyme Inhibitors / isolation & purification*
  • Enzyme Inhibitors / pharmacology*
  • Garcinia / chemistry*
  • Glycoside Hydrolase Inhibitors*
  • Indicators and Reagents
  • Magnetic Resonance Spectroscopy
  • Oxepins / isolation & purification
  • Oxepins / pharmacology*
  • Plant Bark / chemistry
  • Plant Leaves / chemistry
  • Spectrometry, Mass, Electrospray Ionization
  • Spectrophotometry, Infrared
  • Spectrophotometry, Ultraviolet

Substances

  • Benzopyrans
  • Enzyme Inhibitors
  • Glycoside Hydrolase Inhibitors
  • Indicators and Reagents
  • Oxepins