Glycosyltransferases, glycoside hydrolases: surprise, surprise!

Curr Opin Struct Biol. 2008 Oct;18(5):527-33. doi: 10.1016/j.sbi.2008.09.003. Epub 2008 Oct 1.

Abstract

Several in the field-and many outside-consider that solving the three-dimensional structures of more glycoside hydrolases (GHs) and glycosyltransferases (GTs) confines to stamp collection and some even think that there is no main revelation to expect in this area. It is wrong! The past year has come as a refreshing wake-up call with major surprises for both GHs and GTs.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Archaea / enzymology
  • Archaeal Proteins / chemistry
  • Bacterial Proteins / chemistry
  • Catalytic Domain
  • Databases, Protein
  • Glucosyltransferases / chemistry*
  • Glycoside Hydrolases / chemistry*
  • Models, Molecular
  • Protein Conformation

Substances

  • Archaeal Proteins
  • Bacterial Proteins
  • Glucosyltransferases
  • Glycoside Hydrolases