An easy entry to optically active alpha-amino phosphonic acid derivatives using phase-transfer catalysis (PTC)

Chem Commun (Camb). 2008 Sep 28:(36):4345-7. doi: 10.1039/b807027j. Epub 2008 Jul 21.

Abstract

The unprecedented use of phase-transfer catalysis (PTC) in an asymmetric hydrophosphonylation reaction allows the obtainment of a range of optically active alpha-amino phosphonic acid derivatives directly from alpha-amido sulfones.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Imines / chemistry
  • Molecular Structure
  • Organophosphonates / chemical synthesis*
  • Organophosphonates / chemistry
  • Phase Transition
  • Stereoisomerism
  • Sulfones / chemistry*

Substances

  • Imines
  • Organophosphonates
  • Sulfones