Ynol ethers from dichloroenol ethers: mechanistic elucidation through 35Cl labeling

Org Lett. 2008 Oct 16;10(20):4445-7. doi: 10.1021/ol801704u. Epub 2008 Sep 18.

Abstract

The mechanism of ynol ether formation from dichloroenol ethers, a decades-old transformation, has been studied by experimental and theoretical techniques to determine the relative importance of the Fritsch-Buttenberg-Wichell rearrangement (alpha-elimination) and beta-elimination in the evolution of the intermediate carbenoid.