Acute mesenteric ischemia

Hepatogastroenterology. 2008 Jul-Aug;55(85):1349-52.

Abstract

Background/aims: Acute mesenteric ischemia (AMI) is a serious disease in old age with low incidence but with a very high mortality rate (60-70%). The etiology is either primary (embolism or thrombosis of mesenteric arteries or veins, non-occlusive mesenteric ischemia) or secondary (mechanical obstruction such as intestinal volvulus, intussusception, tumor-caused compression). Independent of the origin of the illness, the clinical-pathological picture is the same: intestinal ischemia with subsequent necrosis. The aim of this study was to ascertain which underlying conditions lead to increased probability of development of acute mesenteric ischemia.

Methods: Two hundred and fifteen patients with a primary form of AMI were treated in the years 1991-2007, in the 1st Clinic of Surgery in Brno, Czech Republic and in the Department of General Surgery, Derer's University Hospital in Bratislava, Slovak Republic; the results of the treatment have been statistically evaluated.

Conclusion: The probability of arterial mesenteric ischemia development rises significantly (p < 0.05) in patients with a history of atrial fibrillation and/or myocardial infarction. This probability is also significantly higher in smokers with symptoms of hypertension and clinical signs of abdominal angina (p < 0.05).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Aged
  • Aged, 80 and over
  • Cardiovascular Diseases / complications
  • Cohort Studies
  • Diabetes Complications / complications
  • Female
  • Humans
  • Intestines / blood supply*
  • Ischemia / diagnosis
  • Ischemia / etiology*
  • Ischemia / therapy
  • Male
  • Middle Aged
  • Renal Insufficiency / complications
  • Retrospective Studies
  • Risk Factors