Abstract
A series of novel derivatives of 2'-C-beta-methylcytidine, involving nucleosides modified in the "upper part" of the pyrimidine base (N(4)- and/or 5-position), has been synthesized and evaluated for their inhibitory effect on in vitro replication of the hepatitis C virus and the yellow fever virus (both Flaviviridae).
MeSH terms
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Antiviral Agents / chemical synthesis*
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Antiviral Agents / chemistry
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Antiviral Agents / pharmacology
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Cytidine / analogs & derivatives*
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Cytidine / chemical synthesis
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Cytidine / chemistry
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Cytidine / pharmacology
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Hepacivirus / drug effects
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Yellow fever virus / drug effects
Substances
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Antiviral Agents
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Cytidine