It was in the middle of the 18th century, when Serbia started the process of getting independent from the long-lasting period of the Turkish rule, that the necessity for the organized health care emerged. Despite the fact that it had not existed before, the process advanced rather quickly regarding the contemporary political, social and cultural conditions and the Medical Society of Serbia (MSS) was founded in Belgrade on the 22nd of April, 1872. Although it is known that the doctors from Vojvodina, which was an integral part of Austria of that time, contributed significantly to establishing both the civil and military medical service, this period of our medical history has neither been searched enough nor published in one piece. The author of this paper points out four characteristic activity segments through which the doctors from Vojvodina gave their contribution. An important role in health education and promotion of health culture in the still vassal Serbia was played by the doctors from Vojvodina and popular educators at the very beginnings of the health journalism in Serbian which reached Serbia from Austria. Somewhat later the doctors of Vojvodina went to Serbia to contribute to the establishment and promotion of the civil and military medical services and to take an active part in the Inaugural Meeting and the forthcoming activities of the Medical Society of Serbia. They were also among the initiators and first teachers at the Medical Faculty in Belgrade. This paper highlights and encircles a very important period of our national health culture history by analyzing thoroughly the four above mentioned segments of activities and their protagonists.