Abstract
This paper describes the history and pathogenesis of TRALI and illustrates this with personal experience of the condition over 15 years at a single hospital. It discusses the contribution of transfusion to ALI seen in critically ill patients, and the effect of preventative measures taken in the UK.
Publication types
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Case Reports
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Historical Article
MeSH terms
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Acute Lung Injury / epidemiology
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Acute Lung Injury / etiology*
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Acute Lung Injury / history
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Acute Lung Injury / prevention & control
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Blood Component Transfusion / adverse effects*
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Blood Component Transfusion / history
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Child
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Child, Preschool
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Critical Illness
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Donor Selection / standards
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Female
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HLA-D Antigens / immunology
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History, 20th Century
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History, 21st Century
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Humans
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Incidence
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Isoantibodies / adverse effects
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Isoantibodies / blood
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Leukocytes / immunology
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Male
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Middle Aged
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Parity
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Plasma / immunology*
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Pregnancy
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Prospective Studies
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Randomized Controlled Trials as Topic
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Retrospective Studies
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Sex Characteristics
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United Kingdom / epidemiology
Substances
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HLA-D Antigens
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Isoantibodies