Bone mass gain after parathyroidectomy

Kidney Int. 2008 Sep;74(6):697-9. doi: 10.1038/ki.2008.321.

Abstract

Yajima and co-workers investigated iliac bone biopsies taken before and after parathyroidectomy. They found enhanced de novo osteoid formation and mineral apposition at trabecular sites without signs of previous bone resorption. From this finding they conclude that 'minimodeling' contributes to the increase of bone volume following parathyroidectomy. This report refines our understanding of the compensatory mechanisms by which bone mass and possibly increased mechanical stability of the skeletal apparatus are regained after parathyroidectomy.

Publication types

  • Comment
  • Review

MeSH terms

  • Animals
  • Bone Regeneration*
  • Bone Remodeling
  • Humans
  • Hyperparathyroidism, Secondary / surgery
  • Parathyroid Hormone
  • Parathyroidectomy*
  • Vitamin D

Substances

  • Parathyroid Hormone
  • Vitamin D