Mechanistically inspired design of Fe(III)-TAML peroxide-activating catalysts

J Am Chem Soc. 2008 Sep 17;130(37):12260-1. doi: 10.1021/ja805099e. Epub 2008 Aug 23.

Abstract

Recent broad-ranging mechanistic studies of FeIII-TAML peroxide activators enable a strategy for designing catalysts with improved (i) hydrolytic and (ii) operational stabilities, (iii) faster activation of H2O2 and other peroxides, and (iv) a pH of highest activity closer to 7. Combining all items of insight leads to [Fe{1-NO2C6H3-3,4-(NCOCMe2NCO)2CF2}(OH2)]- (1a) which exhibits the most desirable technical performance in its class.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Catalysis
  • Ferric Compounds / chemistry*
  • Hydrogen Peroxide / chemistry
  • Hydrogen-Ion Concentration
  • Kinetics
  • Lactams, Macrocyclic / chemistry*
  • Models, Molecular
  • Peroxides / chemistry*

Substances

  • Ferric Compounds
  • Lactams, Macrocyclic
  • Peroxides
  • Hydrogen Peroxide