Native hip joint septic arthritis in 20 adults: delayed presentation beyond three weeks predicts need for excision arthroplasty

J Infect. 2008 Sep;57(3):185-90. doi: 10.1016/j.jinf.2008.07.001. Epub 2008 Aug 19.

Abstract

Objectives: Septic arthritis of native hip joints is an uncommon condition in adults in Western Europe, but continues to present a challenge to medical and surgical management. We set out to study the natural history and bacteriology of the disease in this group, with a particular focus on patients requiring excision arthroplasty (EA).

Methods: We retrospectively studied 26 secondary referral cases (20 adults) managed by a specialist bone infection unit over a 12 year period.

Results: Our patient cohort was diverse, affecting all age groups in the presence and absence of co-morbid conditions. The commonest pathogen was Staphylococcus aureus. Of 20 adults studied, five (25%) required EA. Symptom duration prior to presentation was a statistical predictor of the requirement for EA (p<0.003); in particular, symptom duration of over three weeks was strongly associated with requirement for this procedure (p<0.0003).

Conclusions: In cases that present promptly, combined surgical drainage and intravenous antibiotics should be expected to eradicate infection and to salvage the femoral head. Cases presenting following a delay are more likely to require EA and subsequent hip reconstruction.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Arthritis, Infectious / diagnosis*
  • Arthritis, Infectious / pathology
  • Arthritis, Infectious / physiopathology
  • Arthritis, Infectious / surgery*
  • Arthroplasty, Replacement*
  • Child
  • Child, Preschool
  • Europe
  • Female
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Osteoarthritis, Hip / diagnosis*
  • Osteoarthritis, Hip / pathology
  • Osteoarthritis, Hip / physiopathology
  • Osteoarthritis, Hip / surgery*
  • Prognosis
  • Retrospective Studies
  • Staphylococcus aureus / isolation & purification
  • Time Factors