Chitin nanofibril is a new natural raw material obtained from crab and shrimp shells. It is a crystalline polysaccharide capable of interacting with enzymes, platelets, and other cell compounds present in living human tissue. From the first progress studies, it seems that chitin nanofibril helps to maintain cutaneous homeostasis and neutralize the activity of free radicals, and represents a natural carrier that favors the transcutaneous penetration of many active principles.