Intracerebral haemorrhage in primary and metastatic brain tumours

Neurol Sci. 2008 Sep:29 Suppl 2:S264-5. doi: 10.1007/s10072-008-0958-6.

Abstract

Intracerebral haemorrhage may both be a presenting manifestation in unrecognised brain tumour or--more frequently--take place in the disease course of known/suspected brain tumour due to diagnostic/therapeutic procedures, including biopsy, locoregional treatments and anti-angiogenic therapies. Apart from the difficulties inherent to accurate neuroradiological diagnosis in selected cases with small tumour volume, the main clinical problem that neurologists face is represented by decision making in prophylaxis/treatment of venous thromboembolism in these patients. These points are briefly discussed and available evidence on the last point is commented on.

Publication types

  • Review

MeSH terms

  • Angiogenesis Inhibitors / adverse effects
  • Angiogenesis Inhibitors / therapeutic use
  • Anticoagulants / therapeutic use
  • Antineoplastic Agents / adverse effects
  • Antineoplastic Agents / therapeutic use
  • Brain Neoplasms / blood supply*
  • Brain Neoplasms / complications*
  • Brain Neoplasms / pathology
  • Cerebral Arteries / pathology*
  • Cerebral Arteries / physiopathology*
  • Cerebral Hemorrhage / diagnosis*
  • Cerebral Hemorrhage / etiology*
  • Cerebral Hemorrhage / therapy
  • Diagnostic Imaging
  • Humans
  • Risk Assessment
  • Venous Thromboembolism / chemically induced
  • Venous Thromboembolism / drug therapy
  • Venous Thromboembolism / prevention & control

Substances

  • Angiogenesis Inhibitors
  • Anticoagulants
  • Antineoplastic Agents