Water soluble cucurbit[6]uril derivative as a potential Xe carrier for 129Xe NMR-based biosensors

Chem Commun (Camb). 2008 Jun 28:(24):2756-8. doi: 10.1039/b805724a. Epub 2008 May 19.

Abstract

The water soluble cucurbit[6]uril derivative CB*[6] forms a thermodynamically and kinetically stable host-guest complex with xenon in water, the binding affinity of which is about 3 x 10(3) M(-1), comparable to those of cryptophanes, suggesting that it may serve as an effective molecular "carrier" for 129Xe NMR-based biosensors.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biosensing Techniques / methods*
  • Bridged-Ring Compounds / chemistry*
  • Crystallography, X-Ray
  • Imidazoles / chemistry*
  • Kinetics
  • Macromolecular Substances / chemistry
  • Magnetic Resonance Spectroscopy / methods*
  • Molecular Conformation
  • Polycyclic Compounds
  • Solubility
  • Thermodynamics
  • Triazoles / chemistry
  • Water / chemistry*
  • Xenon / chemistry*

Substances

  • Bridged-Ring Compounds
  • Imidazoles
  • Macromolecular Substances
  • Polycyclic Compounds
  • Triazoles
  • cryptophane
  • Water
  • Xenon
  • cucurbit(6)uril