Suicide and attempted suicide are currently considered as an epidemic disease. According to WHO, in the world, one million of individuals commit suicide each year. Every 40 seconds, one person commits suicide and every 3 seconds, one person makes a suicide attempt. Over recent years, the risk of suicide and suicide attempt has considerably increased. Several risk factors have been identified: they are psycho-social, psychopathological, genetic or biological. Suicide is determined by the interaction of all these factors. The purpose of this paper is to present recent data from the literature concerning psychosocial and psychopathological risk factors.