Automated synthesis of lipomannan backbone alpha(1-6) oligomannoside via glycosyl phosphates: glycosyl tricyclic orthoesters revisited

Chem Commun (Camb). 2008 Aug 14:(30):3510-2. doi: 10.1039/b804069a. Epub 2008 May 27.

Abstract

Glycosyl tricyclic orthoesters provide a versatile basis for the efficient generation of glycosyl phosphates, which are used in the automated synthesis of lipomannan backbone alpha(1-6) hexa-mannoside.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alcohols / chemistry*
  • Automation
  • Chromatography, High Pressure Liquid
  • Glucose / chemistry*
  • Lipopolysaccharides / chemistry*
  • Mannosides / chemical synthesis
  • Oligosaccharides / chemical synthesis*
  • Oligosaccharides / chemistry
  • Phosphates / chemistry*

Substances

  • Alcohols
  • Lipopolysaccharides
  • Mannosides
  • Oligosaccharides
  • Phosphates
  • alkoxyl radical
  • lipomannan
  • oligomannoside
  • Glucose