Conjugation of spermine facilitates cellular uptake and enhances antitumor and antibiotic properties of highly lipophilic porphyrins

ChemMedChem. 2008 Aug;3(8):1185-8. doi: 10.1002/cmdc.200800013.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / metabolism
  • Anti-Bacterial Agents / pharmacology*
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / metabolism
  • Antineoplastic Agents / pharmacology*
  • Cell Survival / drug effects
  • Cells, Cultured
  • Humans
  • Hydrophobic and Hydrophilic Interactions*
  • Lipids / chemistry*
  • Molecular Structure
  • Porphyrins / chemistry*
  • Porphyrins / metabolism
  • Porphyrins / pharmacology*
  • Spermine / chemistry*
  • Spermine / metabolism

Substances

  • Anti-Bacterial Agents
  • Antineoplastic Agents
  • Lipids
  • Porphyrins
  • Spermine