Profile of lung cancer in Kashmir, India: a five-year study

Indian J Chest Dis Allied Sci. 2006 Jul-Sep;48(3):187-90.

Abstract

Aim: To study the clinico-pathological aspects of lung cancer, and the outcome of various treatment modalities.

Methods: A retrospective review of histopathologically confirmed lung cancer patients who were registered and treated at our institution over a period of five years was carried out.

Results: A total of 321 patients were studied. There was a preponderance of males (91.9%) as compared to females (8.1%). Smoking history was present in 88% of the male patients. Cough was the main presenting feature in 71.6% of patients. Diagnosis was established by bronchoscopy in 94% of cases. Squamous cell carcinoma was observed in 77.3%, while 17.1% had small cell carcinoma. Radiotherapy formed the main treatment modality alone (22.4%) and in combination (27%). Out of the 321 patients, 206 were evaluable on follow-up. Local failure and distant metastasis were seen in 9.2% and 19.9% of cases, respectively. The overall survival rate of 2, 3 and 5 years was 19.9%, 13.59% and 6.79%, respectively.

Conclusions: . The outcome of lung cancer is poor. Increased survival is possible if the disease is detected early, treated adequately with multi modality approach.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Bronchoscopy
  • Carcinoma, Small Cell / diagnosis
  • Carcinoma, Small Cell / epidemiology*
  • Carcinoma, Small Cell / therapy
  • Carcinoma, Squamous Cell / diagnosis
  • Carcinoma, Squamous Cell / epidemiology*
  • Carcinoma, Squamous Cell / therapy
  • Demography
  • Drug Therapy
  • Female
  • Humans
  • India / epidemiology
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / epidemiology*
  • Lung Neoplasms / therapy
  • Male
  • Middle Aged
  • Radiotherapy
  • Retrospective Studies
  • Treatment Outcome