Inhibition and attention in adolescents with nonmanic mood disorders and a high risk for developing mania

J Clin Exp Neuropsychol. 2009 Jan;31(1):1-7. doi: 10.1080/13803390801945038. Epub 2008 May 6.

Abstract

This study examines psychomotor inhibition, sustained attention, and inhibitory attentional control in adolescents (ages 12-18 years) with a nonmanic mood disorder and with a first-degree relative with bipolar I disorder (MD, N = 20) and demographically matched healthy children of parents without any psychiatric disorder (HC, N = 13). MD participants showed abnormal performance in stop signal reaction time and latency (d = 1.28 and 1.64, respectively), sustained attention response bias (d = 0.75), and color naming speed (d = 0.88). The results indicate that MD participants exhibit psychomotor disinhibition, marginal cognitive slowing and cautious response biases, but no formal deficits in sustained or selective attention.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Anxiety Disorders / complications
  • Attention / physiology*
  • Case-Control Studies
  • Child
  • Family
  • Female
  • Humans
  • Inhibition, Psychological*
  • Male
  • Mood Disorders / physiopathology*
  • Mood Disorders / psychology*
  • Neuropsychological Tests
  • Psychometrics
  • Reaction Time
  • Risk Factors
  • Statistics, Nonparametric