Towards immunotherapeutic drugs and vaccines against multiple sclerosis

Acta Biochim Biophys Sin (Shanghai). 2008 Jul;40(7):636-42. doi: 10.1111/j.1745-7270.2008.00444.x.

Abstract

Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system. Numerous treatment options are available to MS patients; however, these options need to be improved. Herein, we review the current drugs and therapeutic approaches available to MS patients, preclinical trial interventions and recent animal model studies for the potential therapy of MS. Since the current treatment of MS remains elusive and is limited, animal studies and clinical research offers an optimistic outlook.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / immunology
  • Anti-Inflammatory Agents / therapeutic use*
  • Humans
  • Immunologic Factors / immunology
  • Immunologic Factors / therapeutic use*
  • Immunosuppressive Agents / immunology
  • Immunosuppressive Agents / therapeutic use*
  • Multiple Sclerosis / drug therapy*
  • Multiple Sclerosis / immunology
  • Multiple Sclerosis / prevention & control*
  • Peptides / immunology
  • Peptides / therapeutic use*
  • Vaccines / immunology
  • Vaccines / therapeutic use*

Substances

  • Anti-Inflammatory Agents
  • Immunologic Factors
  • Immunosuppressive Agents
  • Peptides
  • Vaccines