Postdiskogram CT features of lidocaine-sensitive and lidocaine-insensitive severely painful disks at provocation lumbar diskography

AJNR Am J Neuroradiol. 2008 Sep;29(8):1455-60. doi: 10.3174/ajnr.A1151. Epub 2008 Jul 3.

Abstract

Background and purpose: At lumbar diskography, intradiskal lidocaine can eliminate or reduce provoked diskogenic pain. The purpose of this study was to evaluate the postdiskogram CT features of lidocaine-sensitive and lidocaine-insensitive severely painful disks.

Materials and methods: Intradiskal lidocaine was injected at 182 severely painful levels in 111 patients. Clinical records/imaging studies were reviewed for response to intradiskal lidocaine (complete/substantial, partial, and no pain improvement), evidence of diskographic contrast leakage (fluoroscopic/CT images), and the overall postdiskogram CT appearance in these severely painful disks. The assessed traditional Dallas grade (degeneration/radial tear [RT]) was supplemented by identified postdiskogram CT features of annular derangement (annular gap [AG], RT into peripheral annular tear [PAT], isolated PAT, lamellar annular tear, free/attached annular fragments, bucket-handle tear, and peripheral annular pocket).

Results: Isolated degenerative changes (40%) and radial defects with or without degeneration (60%) subsets were noted. Dallas grade 3 degeneration was most commonly observed (69%) with increased features of annular derangement in disks with a worsening Dallas grade. Complete/substantial versus no pain improvement was significantly associated with disk state (diskographic leakage, contained), radial defect (none, RT, or AG), and "RT-into-PAT" and were statistically significant in univariate models (P < .001). The associations remained significant in multivariate models. Higher Dallas degenerative grade and presence of free annular fragments were associated with a greater chance of no pain relief.

Conclusion: Severely painful disks demonstrated complex annular derangement with both radial defects (RTs and AGs) or degenerative changes present, alone or in combination. Complete/substantial pain improvement after lidocaine administration is associated with disk state, radial defect (RT and AG), and RT-into-PAT.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Anesthetics, Local / administration & dosage
  • Female
  • Humans
  • Injections, Spinal
  • Intervertebral Disc / diagnostic imaging*
  • Intervertebral Disc Displacement / complications
  • Intervertebral Disc Displacement / diagnostic imaging*
  • Intervertebral Disc Displacement / drug therapy*
  • Lidocaine / administration & dosage*
  • Low Back Pain / diagnostic imaging*
  • Low Back Pain / drug therapy*
  • Low Back Pain / etiology
  • Lumbar Vertebrae / diagnostic imaging
  • Male
  • Middle Aged
  • Pain Measurement / drug effects
  • Tomography, X-Ray Computed / methods*
  • Treatment Outcome

Substances

  • Anesthetics, Local
  • Lidocaine