Experimental infection of cattle with highly pathogenic avian influenza virus (H5N1)

Emerg Infect Dis. 2008 Jul;14(7):1132-4. doi: 10.3201/eid1407.071468.

Abstract

Four calves were experimentally inoculated with highly pathogenic avian influenza virus A/cat/Germany/R606/2006 (H5N1) isolated from a cat in 2006. All calves remained healthy, but several animals shed low amounts of virus, detected by inoculation of nasal swab fluid into embryonated chicken eggs and onto MDCK cells. All calves seroconverted.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Viral / blood
  • Carrier State / blood
  • Carrier State / virology*
  • Cattle
  • Disease Models, Animal
  • Influenza A Virus, H5N1 Subtype / immunology
  • Influenza A Virus, H5N1 Subtype / pathogenicity*
  • Orthomyxoviridae Infections*
  • Respiratory System / virology
  • Virus Shedding

Substances

  • Antibodies, Viral