Syntheses of diheterocyclic compounds based on 2-thioacetohydrazide-5,7-dimethyl-1,2,4-triazolo[1,5-a]- pyrimidine

Zu-Ming Liu; Qiong Chen; Chao-Nan Chen; Hai-Yang Tu; Guang-Fu Yang

doi:10.3390/molecules13061353

Syntheses of diheterocyclic compounds based on 2-thioacetohydrazide-5,7-dimethyl-1,2,4-triazolo[1,5-a]- pyrimidine

Molecules. 2008 Jun 13;13(6):1353-60. doi: 10.3390/molecules13061353.

Authors

Zu-Ming Liu¹, Qiong Chen, Chao-Nan Chen, Hai-Yang Tu, Guang-Fu Yang

Affiliation

¹ Key Laboratory of Pesticide & Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China.

Abstract

The syntheses of some diheterocyclic compounds from 2-thioacetohydrazide- 5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidine (1) are described. Compound 1 can be converted into triazoles, 1,3,4-oxadiazoles, and 1,3,4-thiadiazoles. The structures of the intermediates and the target compounds were confirmed by (1)H-NMR, MS and elemental analyses.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Heterocyclic Compounds / chemical synthesis*
Magnetic Resonance Spectroscopy
Mass Spectrometry
Molecular Structure
Oxadiazoles / chemical synthesis
Pyrimidines / chemistry*
Thiadiazoles / chemical synthesis
Triazoles / chemical synthesis

Substances

Heterocyclic Compounds
Oxadiazoles
Pyrimidines
Thiadiazoles
Triazoles