[Lung protective ventilation - supportive and adjunctive therapies in acute lung injury]

Anasthesiol Intensivmed Notfallmed Schmerzther. 2008 Jun;43(6):464-9; quiz 470. doi: 10.1055/s-2008-1081394.
[Article in German]

Abstract

Various supportive and adjunctive therapies to conventional mechanical ventilation have been evaluated in patients with acute lung injury and acute respiratory distress syndrome (e.g. nitric oxide, prone position, surfactant, glucocorticoids). Although some investigations have shown promising improvements in oxygenation and physiological variables, large randomized trials of adjunctive and supportive therapies showed no impact on survival.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage*
  • Combined Modality Therapy
  • Germany
  • Humans
  • Practice Guidelines as Topic
  • Practice Patterns, Physicians'*
  • Respiration, Artificial / adverse effects*
  • Respiratory Distress Syndrome / etiology*
  • Respiratory Distress Syndrome / prevention & control*

Substances

  • Anti-Inflammatory Agents