Objective: To report the clinicopathologic features of 2 patients with carcinosarcoma of the orbit.
Design: Case reports.
Participants: Two patients with orbital carcinosarcoma were identified.
Methods: Retrospective chart review with clinicopathologic correlation and literature review.
Main outcome measures: Clinical examination, imaging studies, and histopathologic findings.
Results: Two patients, a 56-year-old woman and a 91-year-old woman, with orbital carcinosarcoma were identified. Both tumors contained sarcomatous and carcinomatous components and invaded periorbital structures.
Conclusions: Carcinosarcoma may arise in the orbit or extend into the orbit from the paranasal sinuses. This malignant neoplasm should be aggressively treated with a combination of surgical resection, chemotherapy, and radiation therapy.