A bio-electromechanical imaging technique with combined electrical impedance and ultrasound tomography

Physiol Meas. 2008 Jun;29(6):S63-75. doi: 10.1088/0967-3334/29/6/S06. Epub 2008 Jun 10.

Abstract

Electrical impedance tomography (EIT) seeks to image the electrical conductivity of an object using electrical impedance measurement data at its periphery. Ultrasound reflection tomography (URT) is an imaging modality that is able to generate images of mechanical properties of the object in terms of acoustic impedance changes. Both URT and EIT have the potential to be used in various medical applications. In this paper we focus on breast tumour detection. Both URT and EIT belong to soft field tomography and suffer from the small amounts of available data and the inherently ill-posed nature of the inverse problems. These facts result in limited achievable reconstruction accuracy and resolution. A dual bio-electromechanical tomography system using ultrasound and electrical tomography is proposed in this paper to improve the detection of the small-size tumour. Data fusion techniques are implemented to combine the EIT/URT data. Based on simulations, we demonstrate the improvement of detection of small size anomalies and improved depth detection compared to single modality soft field tomography.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Breast Neoplasms / diagnostic imaging*
  • Computer Simulation
  • Electric Impedance
  • Female
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Phantoms, Imaging
  • Tomography / instrumentation
  • Tomography / methods*
  • Ultrasonography