[Infected pancreatic pseudocysts: technical notes]

G Chir. 2008 Jun-Jul;29(6-7):265-70.
[Article in Italian]

Abstract

Introduction: Starting from the observation of 9 cases of giant infected pancreatic cysts, which occurred from 1994 to 2004 at the Department of Oncological and Surgical Studies, the Authors' aim has been to evaluate whether a more thorough necrosectomy, carried-out under video-endoscopic control, associated with a nose-gastro-cavity tube, which ensures a continuous cleansing of the newly-formed cavity, and an appropriate positioning of the drainages, could reduce the morbidity and allow a shorter recovery of the infected pseudocysts.

Patients and methods: Of 73 cases of acute pancreatitis, observed from 1994 to 2004, 9 showed severe and acute pancreatitis, which included giant pseudocysts, as revealed by the abdomen angio-TC. Our nine septic patients underwent cysto-gastro-anastomosis, necrosectomy, intraoperative cleansing of the cavity with an antibiotic solution and positioning of multiple drainages. Three of these patients also underwent a thorough and targeted necrosectomy, assisted by a trans-anastomotic video-endoscopy. A nose-gastro-cavity tube has been placed in all the patients.

Results: The disappearance of the septic state in our three patients who underwent a targeted video-assisted necrosectomy occurred after three days of treatment; moreover, the abdomen angio-TC on the 5th postoperative day showed the disappearance of the necrotic areas. The recovery of these three patients was significantly shorter, compared to those undergoing traditional treatment (cysto-gastro-anastomosis, standard necrosectomy and positioning of abdominal drainages).

Conclusions: Our surgical video-assisted technique demonstrated that, with a slight increase in the operative time, a better control over sepsis may be accomplished, as well as a reduction of the post-operative morbidity, which leads to shorter hospitalisation of patients with infected pancreatic pseudocysts.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Debridement
  • Drainage
  • Female
  • Humans
  • Injections, Intralesional
  • Male
  • Pancreatectomy
  • Pancreatic Pseudocyst / complications
  • Pancreatic Pseudocyst / drug therapy
  • Pancreatic Pseudocyst / microbiology*
  • Pancreatic Pseudocyst / surgery
  • Retrospective Studies
  • Sepsis* / complications
  • Sepsis* / drug therapy
  • Sepsis* / surgery
  • Treatment Outcome
  • Video-Assisted Surgery / methods

Substances

  • Anti-Bacterial Agents