A carbon-wrapped nanoscaled thermometer for temperature control in biological environments

Nanomedicine (Lond). 2008 Jun;3(3):321-7. doi: 10.2217/17435889.3.3.321.

Abstract

Aims: A carbon-wrapped nanoscaled thermometer for a contactless temperature control in biological systems on the cellular level is presented.

Materials & methods: The thermometer is based on multiwalled carbon nanotubes (MWCNTs) filled with materials with strongly temperature-dependent nuclear magnetic resonance (NMR) parameters. The NMR frequency shift and relaxation time were measured in cuprous-iodide-filled CNTs at different temperatures.

Results: The experimental data indicate a pronounced temperature dependence of the NMR parameters, thereby realizing the nanoscaled thermometer.

Conclusion: This study is a proof-of-concept that the functionalized CNTs can be used as a contactless thermometer in biomedical applications.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biology / instrumentation
  • Equipment Design
  • Equipment Failure Analysis
  • Feasibility Studies
  • Feedback
  • Magnetic Resonance Spectroscopy / instrumentation*
  • Nanotechnology / instrumentation*
  • Nanotubes, Carbon / chemistry*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Thermometers*
  • Transducers*

Substances

  • Nanotubes, Carbon