In vitro, nonrigid model of aortic arch aneurysm

J Vasc Interv Radiol. 2008 Jun;19(6):919-24. doi: 10.1016/j.jvir.2008.02.009. Epub 2008 Mar 24.

Abstract

Purpose: To develop and validate a controlled patient-derived process for producing an in vitro, nonrigid model of aortic arch aneurysm.

Materials and methods: A three-dimensional magnetic resonance (MR) angiogram derived from a patient with an aortic arch aneurysm was segmented by using a homemade software package, meshed and converted to Standard Tessellation Language (STL) file format. The authors transferred this format to a stereolithography machine to produce a replica of the entire aorta, including the arch aneurysm and supraaortic arteries, by pouring silicone rubber.

Results: A sturdy, life-size, soft, transparent plastic cast, accurately reproducing both the internal and external anatomy of the aortic aneurysm, was produced in less than 1 week. Comparison between the STL file format of MR angiographic images of both the patient's aorta and model enabled validation of the reliability of the manufacturing process.

Conclusions: The combination of easy segmentation and conversion to the STL file format with stereolithography techniques enabled a realistic, life-size, silicone vascular phantom to be created from a live patient imaging dataset.

MeSH terms

  • Aortic Aneurysm, Thoracic / diagnosis*
  • Aortic Aneurysm, Thoracic / surgery
  • Computer-Aided Design
  • Humans
  • In Vitro Techniques
  • Magnetic Resonance Angiography*
  • Male
  • Middle Aged
  • Models, Anatomic*
  • Phantoms, Imaging*
  • Silicone Elastomers

Substances

  • Silicone Elastomers