Qualitative and quantitative parametars were evaluated in 186 colorectal cancer patients. Quality of life was evaluated in subgroup of 84 patients. Correlation between Dukes stage of disease and qualitative (gender, blood type, marital status, region of Croatia from where patients were coming) and quantitative biological parametars (age, body mass index) was analysed. There was no statistically significant difference considering distribution of the patients disease stage and gender, blood type, marital status, region of Croatia from where patients were coming and body mass index (p > 0.05). Patients with Dukes D stage of colorectal cancer were statistically significantly younger in comparison to other stages (p < 0.05). Quality of life was the best before surgery, significantly deteriorated immediately after and partially improved three months after the surgery without significant differences between investagted groups with different colorectal cancer stage and type of surgery.